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. 2015 Nov 17;14:196. doi: 10.1186/s12943-015-0464-4

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© van Jaarsveld et al. 2015

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — MiR-634 mimic enhances sensitivity for cisplatin in ovarian cancer cell lines. Ovarian cancer cell lines were transfected with miR-634 mimic or a scrambled control. 48 h after transfection, cisplatin was added and after 24H cell viability was determined with an MTT assay. a Overexpression of miR-634 miRNA in the sensitive A2780 and resistant A2780 DDP cell lines. Error bars represent the standard deviation within one experiment (n = 5). ** = p < 0.01. b Overexpression of miR-634 miRNA in the OV56, TOV21G, OAW42, TOV112D ovarian cancer cell lines. The cisplatin concentration is based on the IC₂₅ value of mock transfected cells). Error bars represent the standard deviation within one experiment (n = 3). * = p < 0.05