Figure 2.

Retinal detachment (RD) induces activation of IL-1β, which is diminished in Rip3-deficient mice. (a) The data show IL-1β levels detected by ELISA at 0 h (non-treated eyes, n=6) and from 6 to 120 h after induction of RD. n=6–9. (b) Western blotting image shows representative data of cleaved IL-1β and β-actin in wild-type (WT) and Rip3^−/− mouse eyes after RD. (-): non-treated eyes. (c) Densitometry analyses of the western blotting data of (b) normalized to the intensity of β-actin (n=4). Data are presented as mean±s.d. *P<0.05, **P<0.01, ***P<0.001