Skip to main content
. 2015 Jan 23;25(2):237–253. doi: 10.1038/cr.2015.9

Figure 2.

Figure 2

Cell depolarization and cell necrosis triggered by cationic carriers in a positive charge-dependent way. (A) A549 cell depolarization caused by cationic particles was determined by diBA-C4-(3) after 1 min of treatment. Heparin (400 μg/ml) was added to neutralize the cationic charge. (B) Percentages of necrotic cells after incubation of A549 cells with liposomes of various zeta-potentials. (C) Cationic charge was neutralized by BSA with concentrations of 40, 80, 160, 640 μg/ml. Data are mean ± SEM; n = 3.*P< 0.05 compared with control group by Student's t-test.