Table 2. Spearman correlations between betatrophin levels and T2D risk factors.
Variables | Non-diabetic | T2D | ||
---|---|---|---|---|
ρ | P-value | ρ | P-value | |
Age (years) | 0.49 | <0.0001 | 0.46 | <0.0001 |
BMI (kg/m2) | 0.14 | <0.0001 | −0.04 | 0.3931 |
Waist/hip ratio | 0.16 | <0.0001 | 0.18 | <0.0001 |
FBG (mmol/L) | 0.19 | <0.0001 | −0.04 | 0.3162 |
HbA1C, % | 0.14 | <0.0001 | 0.02 | 0.6140 |
Insulin (mU/L) | 0.14 | <0.0001 | −0.02 | 0.6680 |
HOMA-IR | 0.17 | <0.0001 | −0.03 | 0.4776 |
HOMA-β | 0.05 | 0.1526 | 0.01 | 0.7070 |
Total cholesterol (mmol/L) | 0.05 | 0.0845 | −0.25 | <0.0001 |
Triglycerides (mmol/L) | 0.15 | <0.0001 | −0.02 | 0.5714 |
HDL cholesterol (mmol/L) | −0.03 | 0.3995 | 0.001 | 0.9819 |
LDL cholesterol (mmol/L) | 0.02 | 0.5426 | −0.27 | <0.0001 |
Diabetes duration (years) | - | - | 0.29 | <0.0001 |
BMI, FBG, T2D: fasting blood glucose ≥7 mmol/l, under treatment, or self-reported of previously diagnosed T2D. Duration of T2D was calculated for subjects with diabetes. Partial Spearman correlation coefficients were adjusted for age, gender, and ethnicity.