Table 2. Spearman correlations between betatrophin levels and T2D risk factors.
| Variables | Non-diabetic | T2D | ||
|---|---|---|---|---|
| ρ | P-value | ρ | P-value | |
| Age (years) | 0.49 | <0.0001 | 0.46 | <0.0001 |
| BMI (kg/m2) | 0.14 | <0.0001 | −0.04 | 0.3931 |
| Waist/hip ratio | 0.16 | <0.0001 | 0.18 | <0.0001 |
| FBG (mmol/L) | 0.19 | <0.0001 | −0.04 | 0.3162 |
| HbA1C, % | 0.14 | <0.0001 | 0.02 | 0.6140 |
| Insulin (mU/L) | 0.14 | <0.0001 | −0.02 | 0.6680 |
| HOMA-IR | 0.17 | <0.0001 | −0.03 | 0.4776 |
| HOMA-β | 0.05 | 0.1526 | 0.01 | 0.7070 |
| Total cholesterol (mmol/L) | 0.05 | 0.0845 | −0.25 | <0.0001 |
| Triglycerides (mmol/L) | 0.15 | <0.0001 | −0.02 | 0.5714 |
| HDL cholesterol (mmol/L) | −0.03 | 0.3995 | 0.001 | 0.9819 |
| LDL cholesterol (mmol/L) | 0.02 | 0.5426 | −0.27 | <0.0001 |
| Diabetes duration (years) | - | - | 0.29 | <0.0001 |
BMI, FBG, T2D: fasting blood glucose ≥7 mmol/l, under treatment, or self-reported of previously diagnosed T2D. Duration of T2D was calculated for subjects with diabetes. Partial Spearman correlation coefficients were adjusted for age, gender, and ethnicity.