Figure 2. Erythrocytes’ p50 is increased in mice deficient in AMPD3.

(A) Representative profiles of oxygen saturation vs oxygen pressure of isolated erythrocytes from WT, Ampd3^−/−, Cd73^−/−, and Ampd3^−/−/Cd73^−/− mice. (B) Quantitative change in isolated erythrocytes from Ampd3^−/−, Cd73^−/−, and Ampd3^−/−/Cd73^−/− p50 value with respect to WT erythrocytes. (C) Erythrocytes 2,3-BPG levels in WT, Ampd3^−/−, Cd73^−/−, and Ampd3^−/−/Cd73^−/− mice. Each plotted point is an individual mouse. P values = *** < .0001.