Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2015 Jul 16;6(7):e1818. doi: 10.1038/cddis.2015.182

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2015 Macmillan Publishers Limited

Cell Death and Disease is an open-access journal published by Nature Publishing Group. This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article's Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

PMC Copyright notice

Aip1 deletion caused ectopic actin accumulations in the cell cortical regions and within lamellipodial protrusions during postnatal testis development. (a and b) Immunostaining of MVH (green) and β-actin (red) of testis tissue sections from P5 control, geAip1^−/− and seAip1^−/− mice. The cells numbered 1–5 in the controls are wild-type germ cells migrating toward the basement membrane. Each arrow points to the migration direction and the polarized protrusion of the numbered germ cell. The cells numbered 6–12 are Aip1-deleted germ cells containing brightly stained actin patches in cell cortical regions. Arrowheads point to Aip1-ablated Sertoli cells with ectopic actin patches. Cell nuclei were stained with DAPI (blue). Scale bars: 10 μm