Figure 2.

Histology of testis, cauda epididymis, and rete testis. +/+, Bscl2^+/+; −/−, Bscl2^−/−. Testes from three to six mice at each time point per genotype were analyzed. Representative images were shown. (a) PND15 Bscl2^+/+ testis. (b) PND15 Bscl2^−/− testis. (c) PND35 Bscl2^+/+ testis. (d) PND35 Bscl2^−/− testis. Data in e–m were from 3- to 6-month-old (3–6 M) males. (e) Bscl2^+/+ testis. (f) Bscl2^−/− testis. (g–j) Enlarged views of Bscl2^+/+ (g and i) and Bscl2^−/− (h and j) seminiferous epithelia to show disorientated distribution of spermatids in the Bscl2^−/− seminiferous epithelia. (k) Number of round spermatids per seminiferous tubule. N=5–6; error bar, S.D.; *P<0.05. (l) Bscl2^+/+ cauda epididymis. (m) Bscl2^−/− cauda epididymis. (o) Bscl2^+/+ rete testis. (p) Bscl2^−/− rete testis. o and p, arrows indicating germ cells. Scale bar, 50 μm