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. 2015 Jul 16;6(7):e1826. doi: 10.1038/cddis.2015.191

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Copyright © 2015 Macmillan Publishers Limited

Cell Death and Disease is an open-access journal published by Nature Publishing Group. This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article's Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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Mutant p53-R273H regulates AKT and BMF expression in a wide range of cancer cells. Cells were transduced with p53si-1 lentiviral shRNA. Protein lysates were isolated for immunoblotting at 72 h after transduction. Note the dephosphorylation of AKT corroborated with BMF induction only in cells bearing p53-R273H.