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. 2015 May 11;5:10101. doi: 10.1038/srep10101

Table 1. Amyloid-like features of aggregated PrPs.

Sequence TEM CR hFTAA ThT kinetics
BoPrP - + + +
HuPrP + + + +
FePrP + + + +
MoPrP + + + +
PoPrP + + + +
HaPrP + + + +
CaPrP + + + +

TEM: Fibrillar structure detected by transmission electron microscopy (Fig. 1)

CR: Displays red green birefringence when stained with Congo red (Fig. 2a)

hFTAA: hFTAA positive aggregates displaying amyloid spectrum when monitored by fluorescence microscope (Fig. 2b)

ThT kinetics: Sigmoidal kinetic profile of ThT fluorescence (Fig. 4b)