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. 2015 Nov 6;7:ecurrents.hd.b966ec2eca8e2d89d2bb4d020be4351e. [Version 1] doi: 10.1371/currents.hd.b966ec2eca8e2d89d2bb4d020be4351e

TRX1 and TMX3 do not decrease levels of thiol-blocked N171-40Q mutant huntingtin.

Fig2

A-B. COS1 cells were co-transfected with plasmids encoding mhtt with cysteines mutated to alanines (N171-40Q-4CA) and TRX1 / TMX3. The letter/number codes above the right western blot lanes are the substitution of the mutant inactive protein. A. TRX1 does not decrease soluble N171-40Q-4CA levels. B. TMX3 increases N171-40Q-4CA levels. n=4. P-values: *<0.05.