eTable 2. Recommended statin doses for adults with chronic kidney disease from stage 3a (glomerular filtration rate below 60 mL/min/1.73 m2, dialysis, kidney transplantation) (30).
Statin | Dosage (mg per day) |
---|---|
Lovastatin | 20*1 |
Fluvastatin | 80*2 |
Atorvastatin | 20*3 |
Rosuvastatin | 10*4 |
Simvastatin/ezetimibe | 20/10*5 |
Pravastatin | 40 |
Simvastatin | 40 |
modified according to Wanner et al. (31).
―Prescribing information lovastatin-ratiopharm (de.oddb.org/de/drugs/fachinfo/uid/26190)
*2ALERT (Assessment of Lescol in Renal Transplantation) study
*3Deutsche Diabetes Dialyse (4D) study
*4AURORA: A Study to Evaluate the Use of Rosuvastatin in Subjects on Regular Hemodialysis: An Assessment of survival and Cardiovascular Events
*5Study of Heart and Renal Protection (SHARP)