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. 2015 Sep 25;47(9):e185. doi: 10.1038/emm.2015.70

Table 1. RKIP-associated miRNAs in cancer.

miRNA Targets Regulation
miR-27a RKIP, CDC27, sFRP1 Chemoresistance, tumor growth.
miR-224 RKIP, ERG-2, p21 Tumor growth, chemoresistance.
let-7 Ras, Myc, BACH1, HMGA1, STAT3 Lin28 inhibits let-7, whereas RKIP inhibits let-7. Inhibition of invasion and metastasis.
miR-200 ZEB1, ZEB2, LOX, HMGA2, EGFR RKIP enhances miR-200 expression. Inhibition of metastasis.
miR-98 ALK4, MMP11, E2F5 miR-98 is positively correlated with RKIP. Inhibition of invasion.