Fig. 7.

FXR silenced cells exhibit increased ECM and SREBP-1 expression, further upregulated by exposure to high glucose conditions. Protein levels of fibronectin (a), type IV collagen (b), and SREBP-1c (c) in FXR silenced cells exposed to 5 mM D-glucose (black solid bar) and 30 mM D-glucose (white empty bar) for 72 h. N = 4–5 per group, *p < 0.05, **p < 0.01