TABLE 3.
Relative mRNA expression of thermogenic mediators in naive TRPV1 WT and KO mice
| Target | Tissue | TRPV1 WT | TRPV1 KO |
|---|---|---|---|
| UCP1 | BAT | 1.02 ± 0.08 | 0.65 ± 0.14 |
| GM | 1.02 ± 0.10 | 1.23 ± 0.51 | |
| UCP2 | BAT | 1.04 ± 0.19 | 1.14 ± 0.31 |
| GM | 1.08 ± 0.26 | 1.01 ± 037 | |
| UCP3 | BAT | 1.01 ± 0.08 | 0.60 ± 0.03*** |
| GM | 1.12 ± 0.21 | 1.40 ± 0.46 | |
| PGC1-α | BAT | 1.01 ± 0.07 | 1.06 ± 0.33 |
| GM | 1.06 ± 0.25 | 0.85 ± 0.18 | |
| PPAR-γ | BAT | 1.18 ± 0.46 | 0.67 ± 0.28 |
| GM | 1.16 ± 0.37 | 0.73 ± 0.32 | |
| Dio2 | BAT | 1.02 ± 0.15 | 0.73 ± 0.31 |
| GM | 1.00 ± 0.05 | 1.01 ± 0.46 |
Results are means ± sem. n = 6, relative to TRPV1 WT mice. ***P < 0.001 TRPV1 KO vs. TRPV1 WT as determined by 2-tailed Student’s t test.