Table 3.

Locations of significant activation contrasting the alcohol- versus water-cue, pre- versus post-priming scans, with and without controlling for alcoholism severity (whole-brain cluster-corrected at Z>2.3, p<0.05). No significant activation was observed for the reverse contrast: post- versus pre-priming.

Pre- vs. Post-Priming
Brain Region	Hemisphere	Cluster Voxels	Max Z	X	Y	Z
Occipital Pole/Lingual Gyrus/Intracalcarine Cortex	L	1977	3.62	−10	−94	−6
- Superior Lateral Occipital Cortex	L		3.42	−30	−80	16
Superior Lateral Occipital Cortex	R	976	4.01	26	−84	16
- Occipital Pole	R		3.37	14	−98	8
- Inferior Lateral Occipital Cortex	R		3.19	36	−82	6
Superior Temporal Gyrus	L	769	3.09	−54	2	−16
- Middle Temporal Gyrus	L		3.08	−52	−44	0
Hippocampus	R	545	3.46	28	−8	−26
- Amygdala	R		3.35	30	2	−22
- Temporal Fusiform Cortex	R		3.13	40	−10	−26
- Temporal Pole	R		3.12	28	6	−28
- Middle Temporal Gyrus	R		3.05	50	−8	−18
- Parahippocampal Gyrus	R		2.95	28	−8	−32
Inferior Frontal Gyrus	L	465	3.85	−54	28	14
Pre- vs. Post-Priming Controlling for Alcoholism Severity
Superior Lateral Occipital Cortex	R	5487	4.01	26	−84	16
- Occipital Pole	R/L		3.68/3.73	14/−10	−98/−94	8/−6
- Superior Lateral Occipital Cortex	L		3.56	−30	−80	16
Middle Temporal Gyrus	L	1464	3.22	−64	−24	−6
- Superior Temporal Gyrus	L		3.13	−56	−12	−8
- Temporal Pole	L		3.11	−54	6	−34
Hippocampus/Amygdala	R	884	3.59	28	−8	−26
- Temporal Fusiform Cortex	R		3.37	42	−10	−26
- Middle Temporal Gyrus	R		3.34	58	0	−24
- Temporal Pole	R		3.33	28	6	−28
Inferior Frontal Gyrus/Orbitofrontal Cortex	L	850	3.77	−54	28	12
- Anterior Prefrontal Cortex	L		3.33	−54	36	−4
Superior Frontal Gyrus	L	399	3.67	−4	28	60

Note: X, Y, and Z MNI coordinates indicate the location of peak voxel activation (or local maxima for subregions) within each cluster. R, right, L, left.