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. Author manuscript; available in PMC: 2016 Nov 1.
Published in final edited form as: Pediatr Blood Cancer. 2015 Jul 14;62(11):2036–2039. doi: 10.1002/pbc.25625

Figure 2. Cytokine responses to IFN-γ stimulation and expression of IFN-γR1 prior and after HSCT.

Figure 2

(A) IL-12p70 production in vitro in response to lipopolysaccharide plus various concentrations of IFN-γ before HSCT. The patient is represented by triangles and a healthy control (HC) with squares.

(B) Expression of IFN-γR1 before HSCT. Whole blood from the patient and from one HC was stained with two IFN-γR1-specific mAbs (dark gray; GIR94 and GIR208) and isotypic control antibodies (pale gray).

(C) IL-12p70 production in vitro response to lipopolysaccharide plus various concentrations of IFN-γ after HSCT as described in (A).

(D) Expression of IFN-γR1 after HSCT. Whole blood from the patient and from a HC was stained with two IFN-γR1-specific mAbs as done in (B). CD14+ monocytes, CD15+ granulocytes and CD19+ B cells were analyzed.