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. Author manuscript; available in PMC: 2015 Nov 18.
Published in final edited form as: Gastroenterology. 2011 Apr 30;141(2):653–662.e4. doi: 10.1053/j.gastro.2011.04.053

Figure 5. CD11b-enriched APC regulate cytokine production.

Figure 5

APC from IL-10 ko Rag2−/− or IL-10 wt Rag2−/− mice were separated into CD11b-enriched (CD11b+) or CD11b-depleted (CD11b−) populations by positive or negative magnetic bead sorting, respectively. Co-cultures contain either IL-10 ko or IL-10 wt splenic CD4+ T cells and CBL-pulsed APC. (A, B) IL-17 or (C, D) IFN-γ was measured in supernatants collected 72 hours after co-culture initiation. Representative results (one of three separate experiments) are shown as mean ± SEM of triplicate culture supernatants. *p< 0.05, **p<0.01.