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. 2015 Nov 1;31(11):1192–1201. doi: 10.1089/aid.2015.0135

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Copyright 2015, Mary Ann Liebert, Inc.

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FIG. 4. — Percentage of clade B and clade C serum samples demonstrating decreased neutralizing activity against glycan-deletion mutant viruses. Clade B and clade C serum samples able to neutralize WT viruses were tested against each of the six matched glycan-deletion mutants for both YU2 (A) and ZM135M.PL10a (B). Data are presented as the percentage of samples from each cohort that exhibited a decrease in ID₅₀ titer against each glycan-deletion mutant virus compared to parental WT virus. ODGC, outer domain glycan cluster; IDGC, inner domain glycan cluster.