FIG 2.

Relative growth rates of the parental strains, the newly generated hybrids, and two commercial lager yeasts at different temperatures (4°C, 8°C, 10°C, 16°C, 30°C, 37°C, and 41°C). Growth rates were calculated as Z-scores. Pairwise similarities were calculated by Euclidean distance, and a UPGMA clustering algorithm was applied to cluster the data. Colors represent the calculated Z-score per strain (as shown in the key), with blue indicating a lower-than-average growth rate, white indicating an average growth rate, and red indicating a higher-than-average growth rate (calculated over the rows). Additionally, plus signs indicate whether a particular strain has a growth capacity that is better than the average growth capacity of all tested strains at a particular temperature (Z-score calculated over the columns; +, between zero and one; ++, above one). Note that some hybrids share the relatively high growth rate at lower temperatures of S. eubayanus with the capacity of S. cerevisiae to grow at temperatures of 37°C and above.