Table 1. Summary of baseline disease characteristics in patients from the biomarker evaluable or non-evaluable population.
Non-evaluable population |
Evaluable population |
|||
---|---|---|---|---|
mFOLFOX6 | Aflibercept plus mFOLFOX6 | mFOLFOX6 | Aflibercept plus mFOLFOX6 | |
(N=57) | (N=49) | (N=60) | (N=70) | |
Gender: male/female | 32/25 | 33/16 | 36/24 | 43/27 |
Age: median (min : max) | 66 (44 : 87) | 62 (29 : 75) | 62 (37 : 81) | 63 (41 : 79) |
Age: <65/⩾65 years | 27/30 | 28/21 | 38/22 | 42/25 |
Race: Caucasian/Asian/Black/other | 41/16/0/0 | 37/11/0/1 | 49/11/0/0 | 60/9/1/0 |
Weight (kg): median (min : max) | 68 (40 : 107) | 70 (40 : 115) | 73 (48 : 134) | 71 (40 : 117) |
BSA (m2): median (min : max) | 1.8 (1 : 2) | 1.8 (1 : 2) | 1.8 (1 : 2) | 1.8 (1 : 2) |
Prior adjuvant chemotherapy: yes/no | 50/7 | 45/4 | 55/5 | 63/7 |
Prior surgery: yes/no | 35/22 | 27/22 | 26/34 | 29/41 |
Prior radiotherapy: yes/no | 53/4 | 47/2 | 57/3 | 62/8 |
ECOG performance status: 0/1/2 | 55/2 | 46/3 | 60/0 | 69/1 |
Number of metastatic organs involved at baseline: 0/1/>1 | 0/16/41 | 0/15/34 | 1/15/44 | 0/12/58 |
Liver-only metastases: yes/no | 15/42 | 20/29 | 18/42 | 14/56 |
Abbreviation: ECOG=Eastern Cooperative Oncology Group.