Table 3.
Example of experimental-based biomarkers of brucellosis
| Biomarker name | Symbol | Importance | Brucella species | PubMed ID |
|---|---|---|---|---|
| Zinc-dependent metallopeptidase | BAB1_0270 | Virulence factor | B. abortus | PMID:24928771 |
| Hypothetical protein | BAB1_0267 | Virulence factor | B. abortus | PMID:24928771 |
| Nucleoside diphosphate kinase | NDP | Vaccine candidate | B. abortus | PMID:25724777 |
| Phosphoribosylamine-glycine ligase | purD | Mutant | B. abortus | PMID:25546140 |
| Amidophosphoribosyltransferase | purF | Mutant | B. abortus | PMID:25546140 |
| ATP-binding/permease protein | cydC | Mutant | B. abortus | PMID:25253663 |
| ATP/GDP-binding protein | looP | Mutant | B. abortus | PMID:25253663 |
| Ribosomal protein L9 | L9 | Vaccine candidate | B. abortus | PMID:23913725 |
| mir-1981 | mir-1981 | Gene regulator | B. melitensis | PMID:22904669 |
| Histidinol dehydrogenase | hisD | Drug target | B. suis | PMID:17481905 |
| Histidinol dehydrogenase | hisD | Drug target | B. suis | PMID:17698620 |
| Beta-carbonic anhydrase | bsCA I | Drug target | B. suis | PMID:20211561 |
| Beta-carbonic anhydrase | bsCA II | Drug target | B. suis | PMID:21251841 |