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The effects of daptomycin on Bacillus anthracis spores. MHBc, DAP, PEN, and CIP represent the control, daptomycin, penicillin G, and ciprofloxacin, respectively. Daptomycin (4 μg/mL) did not kill dormant spores or reduce germination rates; however, the spores were apparently killed as they germinated. The effect of daptomycin is comparable to those of ciprofloxacin (1 μg/mL) and penicillin G (1 μg/mL). The data are representative of those from three independent experiments.
