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. 2013 Dec 30;35(2):257–266. doi: 10.1038/aps.2013.165

Figure 3.

Figure 3

Mangiferin (MA) up-regulated NQO1 expression in HL-60 cells. (A) HL-60 cells were incubated with 50 μmol/L mangiferin for 0, 12, or 24 h. Mangiferin significantly enhanced NQO1 transcription in a time-dependent manner. (B) HL-60 cells were incubated with 50 or 100 μmol/L mangiferin for 24 h. Mangiferin significantly enhanced NQO1 transcription in a dose-dependent manner (real-time RT-PCR). (C) HL-60 cells were incubated with 50 μmol/L mangiferin for 0, 1, 4, 12, or 24 h. Mangiferin significantly increased NQO1 expression in a time-dependent manner in HL-60 cells (western blot). (D) HL-60 cells were incubated with mangiferin (0, 50, 100, or 200 μmol/L) for 24 h. Mangiferin increased NQO1 expression in a dose-dependent manner in HL-60 cells (Western blot). Mean±SD. n=3. bP<0.05, cP<0.01. NQO1, NAD(P)H:quinone oxidoreductase 1.