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. 2015 Nov 18;10(11):e0143082. doi: 10.1371/journal.pone.0143082

Fig 2. Effect of ONC201 on surface TRAIL and DR5 In tumor and normal cells.

Fig 2

(A) Surface TRAIL and DR5 expression in HCT116 (tumor) and HFF (normal) cells following treatment with ONC201 (5 μM, 72 hr, n = 3). IgG was included as an isotype negative control. Doxorubicin (Doxo) is shown as a positive control (1 μg/mL). (B) Surface TRAIL and DR5 in normal fibroblasts following treatment with ONC201 (5 μM) or doxorubicin (1 μg/mL, 72 hr, n = 3). Values (y-axis) is expressed as mean fluorescence intensity.

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