Table 5. Eighteen genes identified by gene co-expression network with k-core algorithm.
Gene symbol | Fertile | Sterile | Dif-k-core | Expression in sterile gonads relative to fertile gonads | ||
---|---|---|---|---|---|---|
Degree | k-core | Degree | k-core | |||
TGFB3 | 1 | 1 | 14 | 8 | -7 | up |
SLC3A2 | 1 | 1 | 9 | 8 | -7 | up |
CYP11A1 | 3 | 2 | 10 | 8 | -6 | down |
DPP4 | 0 | 0 | 7 | 6 | -6 | up |
CPA1 | 3 | 3 | 13 | 8 | -5 | up |
CTSS | 2 | 1 | 10 | 6 | -5 | up |
BCL2L1 | 3 | 3 | 10 | 8 | -5 | down |
CYP21A | 1 | 1 | 7 | 6 | -5 | down |
ABCA1 | 1 | 1 | 6 | 6 | -5 | up |
CXCR3 | 10 | 8 | 15 | 9 | -5 | up |
APOC1I | 1 | 1 | 5 | 5 | -4 | up |
CSF3R | 4 | 4 | 10 | 8 | -4 | up |
CYP17A1 | 3 | 3 | 8 | 6 | -3 | down |
TNFSF10 | 3 | 3 | 7 | 6 | -3 | up |
HSD3β | 5 | 4 | 2 | 2 | 2 | down |
CXCL12A | 11 | 11 | 9 | 8 | 3 | up |
CYP11B2 | 6 | 5 | 3 | 2 | 3 | down |
PRLR | 8 | 5 | 1 | 1 | 4 | down |