Table 3. Effect of Polymyxin and curcumin on body weight, serum urea, and creatinine of 5/6 nephrectomized mice fed on western diet (Nx+WD).

Nx+WD rats were treated with polymixin (Nx+WD+PM) and curcumin (Nx+WD+CU). PM was dissolved in drinking water and freshly prepared CU was given orally everyday by gavage the respective control (Nx+WD+Gavage) received daily gavage of the vehicle. The data shown is the mean and SD of 5 rats per group. Statistically significant difference between the groups are shown in the comments.

	NX+WD	NX+WD+PM	NX+WD+Gavage	NX+WD+CU	Comments
Body weight (gms)	27.52±5.36	25.84±5.20	27.80±4.10	25.60±3.74
Serum Urea(mg/dl)	58.6±15.86	25.95 ±7.96	59.57±13.32	18.61 ±6.205	Nx+WD vs Nx+WD+PM P < 0.01Nx+WD+Gav vs Nx+WD+CUP< 0.001
Serum Creatinine(mg/dl)	0.92±0.09	0.75±0.13	0.98±0.05	0.71±0.07	Nx+WD+Gav vs Nx+WD+CU P < 0.05Nx+WD+PM vs Nx+WD+CUP < 0.05