Table 1. Baseline characteristics of enrolled patients.
Characteristic | H. pylori negative group (n = 124, %) | Eradicated group (n = 122, %) | Persistent group (n = 36, %) | P-value |
---|---|---|---|---|
Mean age (year) a | 68.89 ± 8.78 | 66.64 ± 8.55 | 67.61 ± 8.49 | 0.126 |
Sex | 0.621 | |||
Male | 91 (73.4) | 83 (68.0) | 26 (72.2) | |
Female | 33 (26.6) | 39 (32.0) | 10 (27.8) | |
Smoking | 47 (37.9) | 62 (50.8) | 14 (38.9) | 0.347 |
Alcohol | 58 (46.8) | 62 (50.8) | 20 (55.6) | 0.324 |
Family history of Gastric cancer | 19 (15.3) | 26 (21.3) | 6 (16.7) | 0.462 |
Previous ulcer | 5 (4.0) | 1 (0.8) | 2 (5.6) | 0.793 |
Histology | 0.597 | |||
Low-grade dysplasia | 85 (68.8) | 87 (71.3) | 26 (72.2) | |
High-grade dysplasia | 39 (31.5) | 35 (28.7) | 10 (27.8) | |
Location | 0.418 | |||
Upper 1/3 | 11 (8.9) | 13 (10.7) | 1 (2.8) | |
Middle 1/3 | 53 (42.7) | 40 (32.8) | 17 (47.2) | |
Lower 1/3 | 60 (48.4) | 69 (56.6) | 18 (50.0) | |
Gross appearance | 0.504 | |||
Elevated | 117 (94.4) | 106 (86.9) | 20 (55.6) | |
Flat | 4 (3.2) | 13 (10.7) | 1 (2.8) | |
Depressed | 3 (2.4) | 3 (2.5) | 1 (2.8) | |
Multiplicity | 14 (11.3) | 12 (9.8) | 1 (2.8) | 0.178 |
Maximum diameter of lesion (mm) a | 10.84 ± 7.56 | 11.08 ± 8.87 | 10.55 ± 6.22 | 0.960 |
Metachronous recurrence b | 19 (15.3) | 10 (8.2) | 7 (19.4) | 0.095 |
Dysplasia | 15 (79.0) | 6 (60.0) | 4 (57.2) | |
Cancer | 4 (21.0) | 4 (40.0) | 3 (42.9) | |
Follow up duration (months, median, range) | 53.0 (26.3–85.7) | 58.3 (24.3–85.9) | 57.2 (28.1–85.2) | 0.026 |
Values are presented as mean ± SD or n (%). H. pylori, Helicobacter pylori.
aStatistical significance were tested by oneway analysis of variances among groups
bStatistical significance were tested by Fisher’s exact test between three groups.