Table 3. List of enriched functional annotation groups in 8 clusters by functional annotation clustering analysis.
Cluster | Description for Functional Annotation Groups | Enrichment Score* | No of Genes |
---|---|---|---|
1 | 1. Blood vessel development/morphogenesis | 6.211 | 24 |
2. Ion/cellular chemical homeostasis | 4.421 | 27 | |
3. Positive regulation of protein modification/positive regulation of phosphate (phosphorous) metabolic process | 4.26 | 14 | |
4. Positive regulation of (cellular) proteinmetabolic process | 3.464 | 18 | |
5. Regulation of apoptosis/programmed cell death | 3.354 | 25 | |
6. Regulation of axonogenesis/neuron differentiation | 2.015 | 8 | |
7. Negative regulation of axonogenesis/neurogenesis | 1.515 | 5 | |
8. Negative regulation of apoptosis/programmed cell death | 1.486 | 17 | |
9. Gonad development/ovulation cycle process | 1.37 | 7 | |
10. Mesenchymal cell differentiation/development | 1.347 | 5 | |
2 | 1. Negative regulation of cellular biosynthetic process/cellular metabolic process | 4.926 | 61 |
2. Negative regulation of transcription/RNA metabolic process | 4.269 | 45 | |
3. Neuron projection development/cell morphogenesis | 2.903 | 30 | |
4. Regulation of biosynthetic process/transcription | 1.92 | 161 | |
5. Blood vessel development/morphogenesis | 1.532 | 21 | |
6. Cellular protein catabolic process/proteolysis | 1.53 | 54 | |
7. Positive regulation of cellular metabolic process/biosynthetic process/transcription | 1.456 | 59 | |
8. Mesenchymal cell differentiation/development | 1.446 | 7 | |
3 | 1. Complement activation/B cell mediated immunity | 1.6 | 6 |
2. Positive regulation of protein modification/phosphate (phosphorous) metabolic process | 1.464 | 13 | |
3. Negative regulation of apoptosis/programmed cell death | 1.39 | 21 | |
4 | 1. Nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process/nucleoside phosphate metabolic process | 3.17 | 21 |
2. Proton transport/ATP synthesis coupled proton Transport/ion transmembrane transport | 3.156 | 10 | |
3. Positive regulation of ion transport/regulation of metal ion transport | 2.54 | 10 | |
4. Cellular response to starvation/nutrient levels | 1.873 | 6 | |
5. Negative regulation of apoptosis/programmed cell death | 1.627 | 22 | |
5 | 1. RNA processing/RNAsplicing | 22.144 | 76 |
2. Regulation of gene expression/ macromolecule biosynthetic process | 5.364 | 221 | |
3. Nucleic acid transport/mRNA transport | 2.751 | 15 | |
4. Negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process/ macromolecule metabolic expression/transcription process/gene | 2.132 | 58 | |
5. Cellular glucan metabolic process/polysaccharide metabolic process/energy reserve metabolic process | 2.084 | 8 | |
6 | 1. M phase/mitosis | 3.506 | 28 |
2. Nucleic acid transport/mRNA transport | 3.397 | 13 | |
3. tRNA aminoacylation for protein translation/cellular amine metabolic process | 1.887 | 12 | |
4. Modification-dependent macromolecule catabolic process/protein catabolic process | 1.656 | 35 | |
7 | 1. Protein amino acid glycosylation/glycoprotein biosynthetic process | 2.882 | 16 |
2. Modification-dependent macromolecule catabolic process/protein catabolic process | 1.478 | 37 | |
8 | 1. Blood vessel development/differentiation | 2.862 | 21 |
2. Neuron projection development/cell morphogenesis | 2.222 | 23 | |
3. Positive regulation of cell migration/cell motion | 1.723 | 11 |
*; Functional annotation groups resulted from functional annotation clustering analysis using BP terms were ordered by their mean enrichment score. And, it was considered as significant functional groups that were over 1.3 of enrichment score. Gene symbols used in functional annotation clustering analysis were human orthologues corresponding to probe identifications of Porcine Genome Array.