Table 1.
Baseline Characteristics of all subjects ≥60 years old (n=1,729)
| BMI Category | ||||
|---|---|---|---|---|
| Normal 18.5–25kg/m2 |
Overweight 25–29.9kg/m2 |
Obese ≥30kg/m2 |
p-value | |
| Variable | N=408 | N=747 | N=574 | |
| Age, years | 68.3 ± 5.6 | 68.4 ± 5.2 | 67.1 ± 5.2 | <0.001 |
| Female Sex, % | 303 (74.3) | 405 (54.2) | 357 (62.2) | <0.001 |
| Education Status | ||||
| < High School | 57 (14.0) | 136 (18.2) | 113 (19.7) | |
| Some College | 77 (19.1) | 162 (21.7) | 164 (28.5) | |
| College | 89 (21.8) | 150 (20.1) | 105 (18.3) | <0.001 |
| >College | 185 (45.4) | 299 (40.0) | 192 (33.5) | |
| Yearly Income | ||||
| >$50,000 | 239 (61.1) | 406 (56.6) | 274 (49.9) | 0.002 |
| Marital Status | ||||
| Married | 287 (70.3) | 525 (70.3) | 356 (62.1) | 0.003 |
| Race | ||||
| White | 377 (92.4) | 649 (86.9) | 419 (73.0) | |
| Black | 20 (4.9) | 83 (11.1) | 144 (25.1) | <0.001 |
| Other | 11 (2.7) | 15 (2.0) | 11 (1.9) | |
| Charlson Score | 0.30 ± 0.66 | 0.37 ± 0.80 | 0.59 ± 1.0 | <0.001 |
| Baseline WOMAC Right | 7.5 ± 9.4 | 10.3 ± 12.0 | 14.8 ± 16.3 | <0.001 |
| Baseline WOMAC Left | 7.5 ± 11.8 | 9.9 ± 13.5 | 14.4 ± 16.9 | <0.001 |
| Ever Smoker (y/n) | 186 (45.8) | 387 (52.1) | 285 (50.1) | 0.13 |
| # Medications | 3.32 ± 2.23 | 3.63 ± 2.34 | 4.28± 2.57 | <0.001 |
| Radiographic Knee Osteoarthritis | 197 (48.3) | 456 (61.0) | 412 (71.8) | <0.001 |
| Hip Pain | 32 (7.8) | 83 (11.1) | 72 (12.5) | 0.06 |
| Waist circumference, cm | 90.6 ± 7.7 | 101.4 ± 7.6 | 113.7±10.1 | <0.001 |
| Cohort Allocation* | ||||
| Progression | 63 (15.4) | 205 (27.4) | 214 (37.3) | |
| Incidence | 345 (84.6) | 542 (72.6) | 360 (62.7) | <0.001 |
All values represent mean ± SD, or count (%)
P-value represents the ANOVA across all body mass index categories
OA – defined as having radiographic knee osteoarthritis on either knee or both knees
Some fields may not add up to overall cohort totals due to missing values
WOMAC – Western Ontario and McMaster University Arthritis Index
*
controls were not included in this analysis