Table 3.
Covariates: age, gender, African ancestry proportion (AAs) | ||||||||
---|---|---|---|---|---|---|---|---|
SNP | N Cases* | MAF Cases | N Controls* | MAF Controls | P-value | Odds Ratio | 95% Confidence Interval | |
African American T2D-only (GFR > 60 ml/min) vs population-based controls | rs1952034 | 496 | 0.089 | 1608 | 0.10 | 0.29add | 0.87 | 0.66, 1.13 |
rs12431381 | 497 | 0.098 | 1765 | 0.11 | 0.26add | 0.86 | 0.67, 1.11 | |
rs12434215 | 495 | 0.072 | 1742 | 0.095 | 0.032add | 0.73 | 0.55, 0.97 | |
European American T2D-only (GFR > 60 ml/min) vs population-based controls | rs1952034 | 620 | 0.53 | 752 | 0.55 | 0.40add | 0.93 | 0.79, 1.10 |
rs12431381 | 619 | 0.54 | 746 | 0.57 | 0.12add | 0.88 | 0.75, 1.03 | |
rs12434215 | 620 | 0.55 | 753 | 0.58 | 0.048add | 0.85 | 0.72, 1.00 |
Sample size reflects those with complete clinical and genotypic data
MAF – minor allele frequency.