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. Author manuscript; available in PMC: 2016 Nov 15.
Published in final edited form as: Cancer Res. 2015 Oct 2;75(22):4688–4696. doi: 10.1158/0008-5472.CAN-15-0892

Figure 4. Serum hK2 up-regulation post-RT is associated with biochemical failure in 227 men treated with definitive EBRT for localized prostate cancer.

Figure 4

A. Waterfall plot of percent change in hK2 post-RT compared to baseline.

B. Comparison of biochemical relapse outcomes in men who had an hK2 gain post-RT (n=40) versus those who did not (n=187); (odds ratio 3.39 [95%CI 1.23–9.39], p=0.019).

C. Kaplan-Meier curves for Freedom of PSA progression by Hk2 gain status. Estimates at 72 months for Hk2 gain were 83.5% compared to 94.2% for those without an Hk2 gain (p=0.027).