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. Author manuscript; available in PMC: 2016 Nov 1.
Published in final edited form as: Am J Psychiatry. 2015 Jun 5;172(11):1092–1100. doi: 10.1176/appi.ajp.2015.15010126

TABLE 2.

Hazard Ratio for First Hospitalization for Schizophrenia in Swedish Males As a Function of Level of Smoking and Time Lag From Smoking Assessment to First Possible Hospitalization

Hazard Ratio

Crude Adjusted for
Socioeconomic Statusa
Adjusted for Socioeconomic
Status and Prior Drug Abusea



Time Lag Predictor Variable Estimate 95% CI Estimate 95% CI Estimate 95% CI
0 years Light smoking versus none 2.15 1.25, 3.44 2.05 1.29, 3.27 1.62 1.00, 2.62
Heavy smoking versus none 3.80 1.19, 6.60 3.45 1.97, 6.07 2.21 1.11, 4.42
Neighborhood deprivation (mid versus low) 0.86 0.56, 1.33 0.86 0.55, 1.33
Neighborhood deprivation (high versus low) 1.51 0.89, 2.55 1.40 0.83, 2.36
Low parental education 1.11 0.67, 1.85 1.07 0.65, 1.79
Drug abuse 6.42 3.48, 11.85
1 year Light smoking versus none 2.15 1.33, 3.48 2.04 1.27, 3.29 1.60 0.97, 2.63
Heavy smoking versus none 3.44 1.91, 6.20 3.10 1.70, 5.64 1.96 0.95, 4.06
Neighborhood deprivation (mid versus low) 0.87 0.55, 1.37 0.86 0.55, 1.36
Neighborhood deprivation (high versus low) 1.59 0.93, 2.71 1.47 0.86, 2.51
Low parental education 1.11 0.66, 1.87 1.07 0.64, 1.81
Drug abuse 6.65 3.55, 12.45
3 years Light smoking versus none 2.16 1.26, 3.68 2.05 1.20, 3.49 1.77 1.02, 3.05
Heavy smoking versus none 3.58 1.88, 6.80 3.21 1.65, 6.23 2.39 1.09, 5.24
Neighborhood deprivation (mid versus low) 0.96 0.57, 1.61 0.96 0.57, 1.61
Neighborhood deprivation (high versus low) 1.89 1.03, 3.48 1.80 0.99, 3.29
Low parental education 0.90 0.48, 1.69 0.89 0.47, 1.66
Drug abuse 4.20 1.95, 9.03
a

Adjustment included both family socioeconomic status (as assessed by low parental education) and community socioeconomic status (as assessed by neighborhood deprivation). Adjustment for drug abuse is based on registration for drug abuse in any of several registries (see the online data supplement).