Figure 5.
Effects of genotype on distal femur metaphysis mineralizing perimeter (A), mineral apposition rate (B), bone formation rate (C), osteoblast perimeter (D), osteoclast perimeter (E), bone marrow adiposity (F), and bone marrow adipocyte density (G) in 7-week-old female WT, ob/+, and ob/ob mice. Representative histological sections illustrating differences in bone marrow adiposity and fluorochrome labeling among the 3 genotypes are shown in H-J. Data are mean ± SE. aDifferent from WT, P < 0.05; bDifferent from ob/+, P < 0.05. Scale bar, 200 μm.