Table 3.
Physiological parameters before and after thrombin injection
| Groups | Before thrombin injection
|
1 hour after thrombin injection
|
||||||
|---|---|---|---|---|---|---|---|---|
| pH | PO2 (mm Hg) | PCO2 (mm Hg | MABP (mm Hg) | pH | PO2 (mm Hg) | PCO2 (mm Hg | MABP (mm Hg) | |
| Sham (n=4) | 7.42 ± 0.04 | 216 ± 21 | 20.6 ± | 82 ± 2 | 7.38 ± 0.07 | 219 ± | *30.5 ± | 77 ± 4 |
| 3.5 | 10 | 11.3 | ||||||
| Vehicle (n=4) | 7.39 ± 0.03 | 206 ± 12 | 21.5 ± | 86 ± 6 | # *7.29 ± | 205 ± | *39.1 ± | *74 ± 4 |
| 2.8 | 0.02 | 17 | 6.9 | |||||
| tPA treated (n=4) | 7.39 ± 0.02 | 200 ± 14 | 23.0 ± | 82 ± 1 | # *7.30 ± | 202 ± | *38.6 ± | 76 ± 4 |
| 1.5 | 0.04 | 17 | 5.3 | |||||
Values are mean ± SD. MABP, mean arterial blood pressure (right femoral artery).
indicates p<0.05 between baseline and 1 h after thrombin injection.
indicates p<0.05 compared with Sham group.