Figure 1. DSX, an active component extracted from Erigeron breviscapus, suppressed outward potassium currents in rat retinal ganglion cells.

A: Outward K⁺ currents were induced by a series of depolarizing voltage pulses from a holding potential of -70 mV to +20 mV in an increment of 10 mV in a Ringer's bath solution containing TTX and CdCl₂ (control); B: Extracellular application of DSX (0.1 g/L) significantly suppressed the currents; C: Washout with normal Ringer's solution brought the currents to control level; D: Current-voltage relationship (I-V) curves show voltage-dependent suppression of K⁺ current amplitudes by DSX (n=5).