Table 1.
Sperm parameters of analyzed patients (n = 33) according to AURKC genotype
| Sperm characteristics | AURKC mutation (n = 28) | No AURKC mutation (n = 5) | |||||
|---|---|---|---|---|---|---|---|
| Average | Range | P1a | P2 | P3 | P4 | P5 | |
| Sperm volume (ml) | 2.51 | 0.5–5.2 | 2.2 | 2.5 | 4 | 5 | 2 |
| Sperm concentration (×106 /ml) | 12.52 | 0.62–48 | <0.1 | 6.2 | 11.2 | 8 | 0.7 |
| Progressive Mobility (after 1 h) (%) | 0 | 0 | 0 | 0 | 5 | 12 | 0 |
| Viability (%) | 45.06 | 10–88 | (24/50) | 47 | 67 | 37 | 44 |
| Large-headed spz (%) | 80.42 | 30–100 | (38/50) | 8 | 26 | 45 | 41 |
| Irregular head (%) | 86.48 | 53–100 | (35/50) | 57 | 54 | 79 | 88 |
| Duplicated head (%) | 0.68 | 0–6 | (4/50) | 45 | 38 | 0 | 0 |
| Multiflagellar spz (%) | 44.82 | 15–65 | (14/50) | 28 | 26 | 24 | 5 |
| Abnormal acrosome (%) | 94.85 | 57–100 | (42/50) | 100 | 97 | 95 | 100 |
| Multiple Anomalies Index (%) | 3.52 | 2.80–4.13 | 3.52 | 3.48 | 3.68 | 3.04 | 3.49 |
Spz spermatozoa
aDue to the very low sperm concentration for this patient we analyzed only 50 spz instead of 100