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. 2015 Oct 12;33(33):3894–3902. doi: 10.1200/JCO.2015.61.6672

Table 2.

Change in Pre- to Post-Training Cognitive Scores

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Measure Mean ± SE
P* Effect Size
Intervention (n = 30)
Control (n = 32)
Pretraining Post-Training Change Pretraining Post-Training Change
WISC-IV digit span forward 9.00 ± 0.46 9.93 ± 0.53 0.93 ± 0.59 8.16 ± 0.61 9.00 ± 0.64 0.84 ± 0.37 .897 0.03
WISC-IV digit span backward 8.97 ± 0.51 11.17 ± 0.56 2.20 ± 0.46 8.59 ± 0.53 9.22 ± 0.42 0.63 ± 0.45 .017 0.62
WISC-IV letter-number sequencing 9.87 ± 0.53 11.33 ± 0.36 1.47 ± 0.39 9.47 ± 0.48 10.03 ± 0.53 0.56 ± 0.41 .114 0.41
WISC-IV working memory index§ 95.33 ± 2.32 104.50 ± 2.25 9.17 ± 1.68 92.50 ± 2.52 96.47 ± 2.85 3.97 ± 1.44 .022 0.60
WISC-IV spatial span forward 9.83 ± 0.61 13.13 ± 0.64 3.30 ± 0.71 8.66 ± 0.42 9.91 ± 0.47 1.25 ± 0.39 .012 0.65
WISC-IV spatial span backward 9.50 ± 0.61 12.63 ± 0.55 3.13 ± 0.58 10.03 ± 0.50 10.78 ± 0.48 0.75 ± 0.43 .002 0.84
CPRS-3 inattention 63.73 ± 2.53 56.47 ± 1.39 −7.27 ± 1.91 61.59 ± 2.71 60.88 ± 2.69 −0.72 ± 1.53 .009 0.68
CPRS-3 executive function 62.47 ± 2.43 55.73 ± 1.57 −6.73 ± 1.51 58.97 ± 2.69 59.38 ± 2.48 0.41 ± 1.53 .002 0.84
BRIEF working memory 60.63 ± 2.07 57.23 ± 1.58 −3.40 ± 1.39 60.25 ± 2.53 59.53 ± 2.59 −0.72 ± 1.25 .157 0.36
BRIEF metacognitive index 59.53 ± 2.00 55.53 ± 1.47 −4.00 ± 1.04 57.75 ± 2.28 56.66 ± 2.22 −1.09 ± 1.18 .071 0.47
CPT-II omissions 51.24 ± 2.15 50.46 ± 1.61 −0.49 ± 1.25 50.09 ± 1.64 55.76 ± 2.61 5.67 ± 2.48 .036 0.56
CPT-II hit reaction time 50.26 ± 2.05 48.51 ± 1.69 −2.10 ± 1.47 49.52 ± 1.51 52.05 ± 1.79 2.54 ± 1.25 .020 0.61
WJ-III reading fluency§ 97.57 ± 3.43 99.33 ± 3.43 1.77 ± 1.18 90.29 ± 2.82 94.32 ± 2.91 4.03 ± 1.18 .184 0.34
WJ-III math fluency§ 89.53 ± 2.66 90.43 ± 2.86 0.90 ± 0.84 87.59 ± 2.45 89.25 ± 2.61 1.66 ± 1.24 .620 0.13

NOTE. Boldface indicates statistical significance.

Abbreviations: BRIEF, Behavior Rating Inventory of Executive Function; CPRS-3, Conners' Parent Rating Scale 3; CPT-II, Conners' Continuous Performance Test II; WISC-IV, Wechsler Intelligence Scale for Children–Fourth Edition; WJ-III, Woodcock Johnson III.

*

P values are from repeated-measures analyses of variance examining group × time interaction.

Effect sizes calculated based on group differences in change scores from pre- to post-training using Cohen's d.

Scaled score: mean, 10; standard deviation, 3; higher score is better.

§

Standard score: mean, 100; standard deviation, 15; higher score is better.

Primary intervention outcome.

T score: mean, 50; standard deviation, 10; higher score is worse.