FIG 7.

Regulation of mycolic acid biosynthesis, transport, and regulator genes upon starvation. The WT strain (WT/pGBT), was grown to log phase and was starved for 6 or 24 h before total-RNA sampling. (A) The relative expression of the genes representative of the major steps of the mycolic acid biosynthesis and transport was measured by RT-qPCR. The values are expressed in log₂ as a ratio to values for unstarved log-phase WT cultures. Error bars show SEM from three biological triplicates. P values were <0.05 (*), <0.01 (**), and <0.001 (***).