TABLE 1.
Summary of susceptibility profiles, typing results, and the presence of vanA operon genes in VVE isolates recovered from three patients
| Parameter | Resulta for patient (isolate): |
||||
|---|---|---|---|---|---|
| 1a (a)b | 1a (b)b | 1b (c)c | 2 (d) | 3 (e) | |
| Specimen type | Blood | Blood | Blood | Rectal swab | Rectal swab |
| MIC (mg/liter) of: | |||||
| Ampicillin | >8 (R) | >8 (R) | >8 (R) | >8 (R) | >8 (R) |
| Penicillin | >8 (R) | >8 (R) | >8 (R) | >8 (R) | >8 (R) |
| Daptomycin | 4 (S) | 4 (S) | 4 (S) | 4 (S) | 4 (S) |
| Linezolid | 2 (S) | 2 (S) | 2 (S) | 2 (S) | 2 (S) |
| Vancomycin | 1 (S) | 1 (S) | 1 (S) | 1 (S) | 1 (S) |
| PFGE type | A | A | A | A1 | A |
| ST | 18 | 18 | 18 | 18 | 18 |
| Presence of: | |||||
| vanA gene | + | + | + | + | + |
| vanHAXYZ genes | + | + | + | + | + |
| vanRS genes | − | − | − | − | − |
a
S, susceptibility; R, resistance.
b
Isolate obtained before vancomycin use.
c
Isolate obtained during vancomycin use.