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. 2015 Sep 18;309(10):L1208–L1218. doi: 10.1152/ajplung.00256.2015

Fig. 2.

Fig. 2.

HDE efficiently conditions lung cDCs in vivo to induce Th2 responses. A: CD103+ cDCs (top) or CD11bhi cDCs (bottom) were prepared from the lungs of C57BL/6 mice following airway installation of OVA and either PBS diluent (open bars), Aspergillus protease (Asp, shaded bars), or HDE (solid bars) and cultured with naïve CD4+ OT-II cells to induce Th cell differentiation. Bars represent the means ± SD of duplicate wells. Data are from 1 experiment, representative of 2 experiments. B: CD103+ cDCs (top) or CD11bhi cDCs (bottom) were prepared from the lungs of C57BL/6 mice following airway installation of OVA and either PBS diluent (open bars), polyinosinic-polycytidylic acid [poly(I:C)] (shaded bars), or HDE (solid bars) and cultured with naïve CD4+ OT-II cells to induce Th cell differentiation. Bars represent the means ± SD of duplicate wells. Data are from 1 experiment, representative of 2 experiments. *P < 0.05, **P < 0.01.