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. 2015 Sep 4;21(21-22):2723–2732. doi: 10.1089/ten.tea.2015.0069

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© A. Aijaz et al. 2015; Published by Mary Ann Liebert, Inc.

This Open Access article is distributed under the terms of the Creative Commons Attribution Noncommercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and the source are credited.

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FIG. 3. — Static glucose stimulation of (A) RIN-m and (B) AtT-20ins cells. Trend lines show that glucose secretion from AtT-20ins cells is increasing with increasing glucose. Trend lines fit to RIN-m cells are relatively flat, indicating no response to glucose stimulation. Asterisks show statistically significant differences (p < 0.05) in insulin secretion between incremental glucose concentrations versus control (0 mM). Error bars show standard error of mean. MA, monolayer AtT-20ins cells; MR, monolayer RIN-m cells.