FIG. 8.

Histological analysis of harvested wounds. Hematoxylin and eosin (H & E)-stained wound tissue sections of animals treated with (A) RIN-m microspheres, (B) AtT-20ins microspheres, and (C) empty microspheres (control). Picric Acid Sirius Red (PASR)-stained wound tissue sections of animals treated with (D) RIN-m microspheres, (E) AtT-20ins microspheres, and (F) empty microspheres (control). Quantification of (G) epidermal thickness, (H) dermal thickness, and (I) collagen fiber density. Although there is no statistical difference in dermal thickness between groups, epidermal thickness in treated wounds is statistically greater than control. Collagen fiber densities in treated groups are also statistically greater than control. Asterisks indicate statistically significant differences (p < 0.05) between treated and control wounds. Error bars show standard error of mean. Scale bars = 50 μm. Color images available online at www.liebertpub.com/tea