FIG. 1.

Engineered fibrillar scaffold processing and characterization. (A) Multipolymer fibrillar scaffold design and imaging of fibrous scaffolds through (B) confocal microscopy images of swollen multipolymer scaffolds and (C) SEM images of dry multipolymer scaffolds. Swollen scaffolds had multiple fluorescent dyes encapsulated before electrospinning to enable visualization. Scaffolds were also characterized through quantification of (D) dry fiber diameter (n > 70), (E) degradation (i.e., % mass loss) (n = 4), and (F) bulk compressive moduli (n = 5). HA, hyaluronic acid; HeMA-HA (HH), hydroxyethyl methacrylated HA (degradable fiber component); MeHA, methacrylated HA; PCL, poly(ɛ-caprolactone); SEM, scanning electron microscopy; TB3, transforming growth factor-β3. Color images available online at www.liebertpub.com/tea