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. 2015 Oct 13;21(21-22):2766–2774. doi: 10.1089/ten.tea.2015.0101

Table 1.

Histologic Scores for Repair Groups at 14, 28, and 56 Days

  14 days 28 days 56 days
  Acellular Suture Acellular Cellular BMP2 Suture Acellular Cellular BMP2
Cellularity 3.5 (2, 4) 1 (1, 1) 3 (2, 3) 2 (2, 3) 2 (1, 3) 2 (1, 3) 3 (3, 3) 2 (2, 2) 2.5 (2, 3)
Fibroblasts 2.5 (1, 4) 1 (1, 1) 2 (1, 3) 3 (2, 3) 1.5 (1, 3) 2 (1, 3) 2 (2, 2) 1.5 (1, 2) 2 (1, 3)
Vascularity 3 (2, 4) 3 (3, 3) 2 (2, 3) 2 (2, 3) 3 (2, 4) 2 (2, 2) 2.5 (2, 3) 2.5 (2, 3) 3.5 (3, 4)
Matrix 3 (2, 4) 1.5 (1, 3) 2 (2, 3) 3 (2, 3) 2 (2, 3) 2 (1, 3) 2 (2, 2) 2 (2, 2) 1.5 (1, 2)
Cell orient 3 (1, 4) 1.5 (1, 2) 2 (2, 2) 2 (2, 3) 2 (2, 3) 1.5 (1, 2) 2 (2, 2) 2 (2, 2) 1.5 (1, 2)
Coll. orient 4 (2, 4) 2 (2, 2) 3 (3, 3) 3 (2, 3) 2.5 (1, 3) 2.5 (2, 3) 2 (2, 2) 2.5 (2, 3) 2 (2, 2)
Ins. histo. 3.5 (2, 4) 2 (1, 3) 3 (3, 3) 3 (1, 3) 2.5 (1, 3) 3 (2, 4) 2 (2, 2) 3 (3, 3) 2 (2, 2)
Ins. cont. 4 (2, 4) 2 (2, 3) 3 (3, 3) 3 (2, 3) 2.5 (1, 3) 2.5 (2, 3) 2 (2, 2) 2.5 (2, 3) 2 (2, 2)
Maturity 26.5 (14, 32) 14.5 (12, 17) 20 (19, 22) 22 (15, 23) 18 (12, 24) 17.5 (12, 23) 17.5 (17, 18) 18 (17, 19) 17 (14, 20)

Each outcome was scored from 1 (closest to normal) to 4 (most abnormal). The sum of scores was used as an indication of enthesis maturity (8: normal, 32: furthest from normal). Specifically, cellularity (4: high, 1: low), fibroblasts (4: <25% of total, 3: 26–50%, 2: 51–75%, 1: >75%), vascularity (4: 15 bv/low PF, 3: 11–15 bv/low PF, 2: 6–10 bv/low PF, 1: <6 bv/low PF), matrix (4: minimal, 1: marked), cells parallel (4: <25%, 3: 26–50%, 2: 51–75%, 1: >75%), collagen orientation (4: <25% fibers parallel, 3: 26–50%, 2: 51–75%, 1: >75%), insertion histological findings (4: lacks fibrocartilage/regularity/tidemark, 3: regularity but lacks fibrocartilage/tidemark, 2: regularity and fibrocartilage but lacks tidemark, 1: regularity/fibrocartilage/tidemark present), insertion continuity (4: <25%, 3: 26–50%, 2: 51–75%, 1: >75%). Data are presented as median (range).

BMP2, bone morphogenetic protein 2; bv, blood vessels; PF, power field.