Table 1. Demographics, biochemical and clinical markers for the PCOS and control group (unpaired t test).
| Normal n = 25 | PCOS n = 25 | P value | |
|---|---|---|---|
| Mean (SD) | Mean (SD) | ||
| Age (years) | 32.2(7.7) | 32.1(9.0) | 0.97 |
| Weight (kg) | 76.0(18.8) | 77.4(16.3) | 0.79 |
| BMI (kg/m2) | 27.1(5.8) | 28.8(5.4) | 0.31 |
| Fasting glucose (mmol/l) | 4.7(0.4) | 4.8(0.6) | 0.56 |
| 2 Hour glucose (mmol/l) | 4.9(1.2) | 5.7(1.3) | 0.06 |
| Androstenedione (nmol/l) | 8.4(5.1) | 10.7(6.7) | 0.25 |
| ALT (IU/L) | 24.3(14.4) | 23.3(12.7) | 0.79 |
| Insulin (μU/ml) | 6.8(3.7) | 10.2(6.4) | 0.03 |
| HOMA-IR | 1.5(0.9) | 2.3(1.7) | 0.07 |
| HOMA-β | 38.4(66.1) | 158.8(89.7) | 0.001 |
| Testosterone (nmol/L) | 1.2(0.7) | 2.3(1.6) | 0.03 |
| SHBG (mmol/L) | 81.8(105.8) | 52.6(53.1) | 0.29 |
| FAI | 2.6(1.7) | 11.1(18.9 | 0.13 |
| hsCRP (mg/l) | 2.3(3.8) | 2.8(3.9) | 0.65 |
| miR-93 expression (relative to control group) | 1.0(0.6) | 2.0(1.6) | 0.009 |
| miR-223 expression (relative to control group) | 1.0(0.7) | 2.01(2.2) | 0.029 |
(BMI, body mass index; FAI, free androgen index; SHBG, sex hormone binding globulin; HOMA-IR, homeostatic model assessment-insulin resistance; HOMA-β, homeostatic model assessment-insulin beta cell sensitivity; hsCRP, high sensitivity C-reactive protein.).