Table 2.
Hematology parameters of female B6C3F1 mice dermally exposed to dimethyl carbonate for 28 days.
| Dimethyl carbonate |
||||
|---|---|---|---|---|
| Parameter | 0% | 50% | 75% | 100% |
| Hemoglobin (g/dl) | 13.84 ± 0.26 | 12.82 ± 0.79 | 13.50 ± 0.63 | 13.84 ± 0.76 |
| Erythrocytes (M/μl) | 8.96 ± 0.22 | 8.35 ± 0.50 | 8.59 ± 0.43 | 8.85 ± 0.50 |
| Platelets (K/μl) | 291 ± 131 | 471 ± 92 | 297 ± 101 | 384 ± 63 |
| Hematocrit (%) | 47.36 ± 1.05 | 43.74 ± 2.79 | 44.68 ± 2.26 | 46.40 ± 2.78 |
| MCV (fl) | 52.84 ± 0.21 | 52.32 ± 0.30 | 52.02 ± 0.12 | 52.40 ± 0.27 |
| MPV (fl) | 5.66 ± 0.32 | 5.52 ± 0.65 | 5.28 ± 0.44 | 4.80 ± 0.28 |
| MCH (pg) | 15.46 ± 0.12 | 15.36 ± 0.12 | 15.70 ± 0.17 | 15.68 ± 0.11 |
| MCHC (g/dl) | 29.22 ± 0.21 | 29.32 ± 0.19 | 30.26 ± 0.35 | 29.88 ± 0.24 |
| PDW (%) | 23.02 ± 1.06 | 20.24 ± 1.09 | 22.80 ± 1.81 | 22.86 ± 1.13 |
| Leukocytes (K/μl) | 7.00 ± 1.34 | 6.64 ± 1.51 | 7.75 ± 1.42 | 7.26 ± 1.37 |
| % Lymphocytes | 74.62 ± 2.50 | 73.90 ± 3.08 | 81.94 ± 1.15 | 73.87 ± 3.48 |
| % Neutrophils | 20.39 ± 1.95 | 20.39 ± 2.29 | 14.93 ± 1.15 | 21.44 ± 2.13 |
| % Monocytes | 3.76 ± 0.31 | 3.81 ± 0.37 | 2.57 ± 0.33 | 2.80 ± 0.42 |
| % Eosinophils | 1.09 ± 0.37 | 1.57 ± 0.55 | 0.69 ± 0.20 | 1.37 ± 0.85 |
| % Basophils | 0.15 ± 0.05 | 0.34 ± 0.13 | 0.07 ± 0.03 | 0.52 ± 0.31 |
MCH, mean corpuscular hemoglobin; MCV, mean corpuscular volume; MPV, mean platelet volume; PDW, platelet distribution width; MCHC, mean corpuscular hemoglobin concentration.
Values are expressed as the means (± SE) for each group.