Table 1.
Schedule of assessments
| M0 | M6 | M12 | M18 | M24 | M30 | M36 | |
|---|---|---|---|---|---|---|---|
| Demographics | X | ||||||
| Medical history | X | ||||||
| Associated pathologies and treatments | X | X | X | X | X | X | X |
| Vital signs, clinical examination | X | X | X | X | X | X | X |
| ADL | X | ||||||
| MMSE | X | X | X | X | X | ||
| DSM IV Criteria | X | ||||||
| NEUROPSYCHOLOGICAL TESTS | X | X | X | X | X | ||
| - Free and Cued Selective Reminding | |||||||
| -Test Trail Making Test A & B | |||||||
| -Verbal Fluency | |||||||
| -WAIS-R coding | |||||||
| - Visual Analogue Scale | |||||||
| CDR | X | X | X | X | X | ||
| GDS | X | X | X | X | X | ||
| FUNCTIONAL TESTS | X | X | X | X | X | ||
| - Fried’s criteria | |||||||
| - SPPB | |||||||
| IADL | X | X | |||||
| ADCS-ADL PI | X | X | X | X | X | ||
| Health-economics evaluation | X | X | X | X | X | X | X |
| Biology | X | X | X | X | X | ||
| Biological collection | X | X | X | X | |||
| Fatty acid profile | X | X | |||||
| Compliance | X | X | X | X | X | X | X |
| MRI | X (M0 or M6) | X | |||||
| FDG-PETscans (monocentric) | X | X | X | ||||
| AV45- PETscans | X* | X* | X* | X* | X* | ||
| Adverse events | X | X | X | X | X | X | X |
*
AV45 PET scans were proposed either at M0, M6, M12, M18 or M24