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. Author manuscript; available in PMC: 2016 Jul 1.
Published in final edited form as: NMR Biomed. 2015 May 18;28(7):873–880. doi: 10.1002/nbm.3316

Figure 1.

Figure 1

(A) Pulse sequence diagram for 2D UTE-MT imaging: UTE acquisition with a minimal nominal TE of 8 μs is preceded by a Fermi (8 ms in duration) saturation pulse centered off the water peak to selectively saturation bound water with a shorter T2* with little effect on pore water with a longer T2*. (B) Diagram showing three pools of protons in cortical bone: tightly bound water and collagen backbone protons are selectively suppressed by the MT pulse with a high MT frequency offset (Δf). Loosely bound water is suppressed with a lower Δf. The efficiency of MTR is related to the MT pulse power (θ).