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. 2015 May 19;6(24):20084–20098. doi: 10.18632/oncotarget.3907

Figure 1. Chemical structure of embonic acid (EA) and inhibitory effect of EA on human m-NAD(P)-ME and c-NADP-ME.

Figure 1

A. Chemical structure of EA. B. The assay mixture contained 40 mM malate, 10 mM MgCl2, 2 mM NAD+ or NADP+ and 50 mM Tris-HCl (pH 7.5) with various concentrations of EA. The concentrations of EA ranged from 0 to 75 μM. Closed circles, m-NAD(P)-ME; open circles, c-NADP-ME.