Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
| Characteristics | m-NAD(P)-ME | Embonic acid |
|---|---|---|
| WT | 1.4 ± 0.4 μM | |
| Tetramer interface mutant | H142A/D568A | 2.1 ± 0.1 μM |
| Exo site mutant(at tetramer interface) | R197E | 2.8 ± 0.1 μM |
| R542V | 1.5 ± 0.2 μM | |
| Dimer interface mutant | Q51A/E90A | 29.5 ± 7.4 μM |
| Fumarate site mutant(at dimer interface) | E59N | 5.1 ± 0.7 μM |
| R67A | >75 μM | |
| R91A | >75 μM | |
| R67A/R91A | >75 μM | |
| K57S/E59N/K73E/D102S | >75 μM |
